Computational Bioinformatics

Schedule

Schedule

Below is a tentative schedule of covered topics and associated activities. The schedule is subject to change with the addition of guest appearances.

Week Topic Reading
1 Introduction to the course, careers Read the syllabus
1 No lab N/A
2 DNA Basics, Central Dogma of Biology, Replication of DNA and other basics, Activity 01 Chap 1
2 Lab: Software Tools See GitHub repository
3 BioPython Basics, Activity 02 Chap 1
3 Lab: BioPython and Silent Mutations Hand out
4 Reading Frames, Mutations, Begin Sequence Alignment, Activity 03 Chap 2, 3
4 Lab: Tool Intro And Presentation Hand out
5 Sequence Alignment, Needleman-Wunsch algorithm (Global Alignment) Chap 3
5 Lab: No new assignment Hand out
6 Biopython and Sequence Alignment, Activity 04 Chap 3, Chap 4, HandOut
6 Lab: seq Analysis Hand out
7 Fall Break; No Class
7 No lab N/A
7 Activity 05 BuildADatabase
8 Blast and protein blast Chapters 4 and 5
8 Lab: article and tool Hand out
9 SubMatrices: Pam and BLOSUM. Test Week: Activity 06 (video)
9 Lab: See last week’s lab
10 Gene Assembly Activity 07 Chapter 8 and 9
10 Lab: Ethics in Bioinformatics Research Hand out
11 Protein research websites Activity 08
11 Lab: Hand out
12 Final project assignment
12 Lab: Hand out
13 Thanksgiving
14 Activity 09 and Activity 10
14 Lab: Hand out
15 BeagleTM
16 Course Summary
16 Presentations
16 Presentations